Longevity Intervention Database


Database Top list ITP ITP (females) ITP (males)
Top list
longevity interventions		 Rats
Strain F344		 Rats
Other strains		 Mice
Strain HET3		 Mice
Strain C57BL6		 Mice
Other strains		 Fruit flies
Strain Canton S		 Roundworms
Strain N2		 Roundworms
Other strains
Rapamycin

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

28%

22%

21%

11%

7%

14%

19%

8%

77%

17%

117%

18%

 

 

 

 

20%

19%

11%

11%

Rapamycin + Acarbose

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

28%

37%

21%

24%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Metformin + Rapamycin

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

23%

23%

17%

10%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Acarbose

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

5%

22%

8%

12%

 

 

 

 

 

 

 

 

 

 

 

 

30%

7%

11%

5%

Captopril

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

5%

14%

8%

7%

 

 

 

 

 

 

 

 

 

 

 

 

48%

46%

 

 

Protandim

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

3%

7%

6%

6%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Candesartan cilexetil

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

1%

4%

7%

1%

 

 

 

 

 

 

 

 

 

 

 

 

4%

5%

 

 

Methylene blue

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

2%

-2%

6%

-5%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Simvastatin

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

4%

4%

4%

3%

 

 

 

 

 

 

 

 

 

 

 

 

68%

51%

 

 

Resveratrol

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

4%

7%

3%

2%

 

 

 

 

 

 

 

 

 

 

 

 

85%

79%

84%

77%

Oxaloacetic acid

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

3%

4%

3%

3%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

1,3-butanediol

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

1%

9%

4%

4%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Canagliflozin

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

1%

14%

4%

10%

 

 

 

 

 

 

 

 

 

 

 

 

21%

45%

 

 

Glycine

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

4%

6%

2%

5%

 

 

 

 

 

 

 

 

 

 

 

 

23%

10%

 

 

Hydrogen sulfide donor

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

1%

2%

4%

3%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Geranylgeranyl acetone

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

2%

5%

3%

2%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Caffeic acid phenethyl ester

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

5%

3%

1%

-1%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Leucine

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

-1%

0%

5%

-1%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Maximum lifespan:

 

 

 

 

 

 

 

 

2%

-1%

3%

2%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Green tea extract

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

7%

5%

-1%

1%

 

 

 

 

 

 

 

 

 

 

 

 

6%

12%

33%

29%