Longevity Intervention Database


Database Top list ITP ITP (females) ITP (males)
Top list
longevity interventions		 Rats
Strain F344		 Rats
Other strains		 Mice
Strain HET3		 Mice
Strain C57BL6		 Mice
Other strains		 Fruit flies
Strain Canton S		 Roundworms
Strain N2		 Roundworms
Other strains
Rapamycin + Acarbose

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

28%

37%

21%

24%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Acarbose

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

5%

22%

8%

12%

 

 

 

 

 

 

 

 

 

 

 

 

30%

7%

11%

5%

Rapamycin

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

28%

22%

21%

11%

7%

14%

19%

8%

77%

17%

117%

18%

 

 

 

 

20%

19%

11%

11%

Metformin + Rapamycin

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

23%

23%

17%

10%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

17-a-estradiol

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

2%

19%

0%

12%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Canagliflozin

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

1%

14%

4%

10%

 

 

 

 

 

 

 

 

 

 

 

 

21%

45%

 

 

Captopril

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

5%

14%

8%

7%

 

 

 

 

 

 

 

 

 

 

 

 

48%

46%

 

 

Astaxanthin

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

3%

12%

-1%

6%

 

 

 

 

 

 

 

 

 

 

 

 

15%

15%

 

 

16-a-hydroxyestriol

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

-7%

15%

-4%

4%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Nordihydroguaiaretic acid

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

1%

12%

2%

5%

 

 

 

 

 

 

 

 

 

 

 

 

0%

-16%

33%

7%

Halofuginone

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

0.2%

8.8%

-0.3%

6.9%

 

 

 

 

 

 

 

 

 

 

 

 

33%

4%

 

 

Meclizine

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

3%

8%

1%

6%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Protandim

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

3%

7%

6%

6%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Maximum lifespan:

 

 

 

 

 

 

 

 

-4%

9%

-2%

4%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

1,3-butanediol

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

1%

9%

4%

4%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Forskolin

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

0.8%

8.3%

0.5%

4.4%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Epicatechin

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

-2.2%

5.3%

0.2%

6.2%

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Aspirin

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

1%

8%

1%

4%

 

 

 

 

 

 

 

 

 

 

 

 

49%

33%

13%

8%

Glycine

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

4%

6%

2%

5%

 

 

 

 

 

 

 

 

 

 

 

 

23%

10%

 

 

Mitoglitazone

Median lifespan:

Maximum lifespan:

 

 

 

 

 

 

 

 

-2.3%

8.7%

-3.9%

2.9%